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Add to cart. It is also recommended that the reader take a look at my five other newsletters on living in a toxic world. Many of the topics e. Haas, E.

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Staying healthy with nutrition: The complete guide to diet and nutritional medicine. Berkeley, CA: Celestial Arts. Houlihan, J.

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Mowrey, D. B The scientific validation of herbal medicine: How to prevent disease with herbs, vitamins, minerals and other nutrients. Thornton, J. Biomonitoring of industrial pollutants: Health and policy implications of the chemical body burden. Public Health Reports, , July-August, pp. Industry releases annually billion of pounds of toxic chemicals into the environment, contaminating the land, air, water and ultimately our bodies.

Body Burden The concept of body burden is a useful way for to think and talk about the extent to which humans are contaminated with synthetic chemicals found in the air, water, land and food, upon which they rely for survival and good health. Detoxification Although it is effective in eliminating by-products from natural metabolic processes, the detoxification system of the human body is often rendered ineffective in coping with the chemical pollution in people.

Detoxification Defined Haas provides a useful definition of detoxification. Detoxification Systems of the Human Body Humans evolved as a species with an elegant and effective detoxification system.

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Signs and Symptoms of Toxicity There are a host of signs and symptoms of toxicity including but not limited to headaches, joint pain, fatigue, allergies, environmental sensitivity, mucous buildup, fever, constipation, indigestion, anxiety, depression, mood swings, nervousness, sleepiness, insomnia, sinus congestion, runny nose, coughing, wheezing, sore throat, poor circulation, cognitive deficits, immune weakness and being prone to disease and sickness, among various other signs and symptoms see Haas, Health Benefits of Detoxification The depth and breadth to which the land, water, air, human food supply and day-to-day consumer products are contaminated with synthetic chemicals make it clear that we live in a toxic world and the general population is at risk for carrying a body burden of synthetic chemicals.

Purification of the Blood One general herbal therapy that can serve as a key strategy in detoxifying the cells, tissues and organs of the body is blood purification using alteratives i. Functions of Blood Basically, blood performs the three main functions of transportation, regulation and protection, all of which are responsible for sustaining life and preserving good health. Burdock Root Arctium lappa Burdock root is long recognized as an overall blood purifier and blood building herb, with additional diuretic and diaphoretic activity, and, thereby, cleansing the body of toxins and wastes in three fundamental ways.

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Dandelion Root Taraxacum offcinale Dandelion root serves as a primary blood purification herb because of its ability to filter toxic chemicals from the bloodstream. Echinacea Root Echinacea augustifolia An important function of echinacea root is to stimulate the lymphatic system so it can help clear and cleanse toxic substances from the body.

Licorice Root Glycyrrhiza glabra Licorice root is recognized in across different cultures to possess detoxification properties. Yellow Dock root Rumex crispus Yellow dock root serves the liver function quite well by enhancing its ability to filter the blood and stimulating the production of bile. Herbal Detoxification Formulas Unless you have the knowledge and ability to prepare your own herbs or know an herbalist who can create a detoxification formula, there are any number of herbal supplement formulas designed for cleansing and detoxifying the body, generally, and blood, specifically.

Conclusion We live in toxic world. References Haas, E. Tierra, M. Saller In a Cochrane review of 18 randomized clinical studies assessing use of milk thistle versus placebo or no intervention in patients with alcoholic or hepatitis B or C virus liver disease, milk thistle had no significant effects on mortality, complications of liver disease, or liver histology. Liver-related mortality was significantly reduced by milk thistle when all trials were assessed relative risk [RR], 0.

Rambaldi In some trials, a reduction in serum transaminases was demonstrated but with no effect on liver histology or clinical progression. Ferenci , Mayer , Saller Symptoms related to biliary retention resolved faster in 1 subsequent trial, but with no effect on quality-of-life measures.

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El-Kamary One small, open-label study in viral hepatitis demonstrated a reduction in viral load with high-dose intravenous IV administration of silibinin. Yang The Hepatitis C Antiviral Long-Term Treatment against Cirrhosis trial assessed the long-term use of silymarin in 1, patients with advanced fibrosis or cirrhosis after peginterferon and ribavirin therapy had failed.

Use of silymarin was associated with less fibrosis as measured by the Ishak fibrosis score, but this association was not noted for clinical outcome measures. Freedman The American Association for Study of Liver Disease AASLD practice guidelines for primary biliary cirrhosis and primary biliary cholangitis state that the addition of silymarin to ursodeoxycholic acid provided no additional benefit. Lindor , Lindor A meta-analysis evaluated English and Chinese randomized placebo-controlled trials from to December to determine the safety and efficacy of silymarin as monotherapy and combination therapy for treatment of chronic hepatitis B.

However, when silymarin was combined with these agents, serum indices and hepatic markers were reduced.

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Although the majority of studies were of poor quality, the positive synergistic effect is an important finding that can help inform future clinical studies. Wei In patients with hepatitis C, beneficial effects have not been noted with use of silymarin. In a multicenter, double-blind, placebo-controlled trial, patients with chronic hepatitis C and elevated ALT levels who were unsuccessfully treated with interferon, silymarin mg or mg 3 times daily for 24 weeks did not significantly reduce ALT levels.

Fried In a study of children 5 to 16 years of age with nonalcoholic fatty liver disease, silymarin given for 12 weeks improved fatty liver infiltration, liver function tests, and triglyceride levels; however, LDL and HDL cholesterol levels were not altered. Famouri Milk thistle may be useful in acute hepatotoxicity due to amatoxin poisoning from ingestion of Amanita phallides or other Aminata mushrooms.

Mechanisms include saturating receptor sites on liver cell membranes before the alpha-faloidine and alpha-amanitin toxins can bind and enter the cell. Mengs Blood transfusions are the cornerstone of treatment for patients with thalassemia. In turn, patients can develop iron overload, leading to oxidative stress and organ damage. Moayedi Esfahani Milk thistle has been suggested to be an iron chelator and has been evaluated in thalassemia for its ability to mitigate these effects.

Neopterin, a marker of cellular immune system activation, and TNF-alpha were decreased in both groups after silymarin therapy, whereas production of interferon-gamma and IL-4 were increased. No adverse effect on frequency or function of immune cells was observed. These data indicate recovery of immune status and cytokine production. Gharagozloo Treatment was well tolerated with no reported adverse effects. Darvishi-Kherzi Additionally, varicocelized rats receiving silymarin had higher testosterone levels and a larger percentage of sperm with nuclear maturity compared with varicocelized rats not receiving treatment.

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Moshtaghion A dose of mg of silymarin 3 times daily has been suggested for hepatic cirrhosis. Flaig , Ramasamy A preparation consisting of mL of boiling water poured over 3. Blumenthal Consumption of silymarin in the form of tea may not be effective, as silymarin is poorly soluble in water. Awang Deep , Greenlee Caution should be used in pregnant and breastfeeding women. In vitro and animal studies suggest potentially beneficial effects with milk thistle in pregnancy. In a study of rats receiving ethanol during specific weeks of the gestational period, coadministration of silymarin with ethanol resulted in no deficits in spatial working memory in rats on postnatal day 60, suggesting silymarin provided a protective effect against alcohol-induced learning issues.

Neese In a study of peripheral blood mononuclear cells from preeclamptic women, silibinin inhibited nuclear factor kappa B activation and production of inflammatory cytokines. Giorgi Milk thistle may possess galactagogue effects by increasing prolactin levels. Dietz A study evaluated the efficacy and safety of silymarin to promote milk production in 50 women who had elected to stop breastfeeding because their infants did not consume the milk.

Milk production was enhanced with no change to its chemical composition. Di Pierro Antiretrovirals: Milk thistle may reduce the efficacy of protease inhibitors, integrase inhibitors, and non-nucleoside reverse transcriptase inhibitors. Caution and close monitoring is warranted if using these agents concomitantly with milk thistle.